The Astros have more wins against the Angels than any other opponent this season and will look to move to 10-7 against their divisional foes when they begin a three-game set Friday.
As the Astros look for their first four-game winning streak since June 12-16, they will hand the ball to Dallas Keuchel.
The left-hander is 1-3 with a 5.54 ERA in his last six starts and is coming off his shortest start of the season as he allowed five runs in 3 1/3 innings against Oakland.
"I felt like the slider was keeping them in check early in the count because they like to hack," Keuchel said after the outing. "Some of those base hits were just because they're strong enough to get them through the hole. It's just one of those days where nothing was going right, and everything was going wrong."
Meanwhile, the Angels will counter with a left-hander of their own.
Jason Vargas was stuck with a no-decision Sunday, but he pitched well as he limited the Rangers to two runs in six innings, while striking out eight.
"Jason did a great job," Angels manager Mike Scioscia said. "It's a tough lineup to get through, and it's hot. He needed a lot of pitches to get through five, but felt strong enough to finish six and looked good in the sixth inning."
Angels: Trout reaches 100 runs
Mike Trout is in his second Major League season, and for the second time, he has scored more than 100 runs.
Trout reached the 100 run mark Wednesday and became the seventh player to score more than 100 runs in his age-20 and age-21 seasons.
"Last year was incredible because he did it minus 100 at-bats that he didn't have in the month of April," Scioscia said. "And that's off the charts what he did last year. I think this year his numbers are going to be terrific. He's having an incredible year. And I don't think it's under the circumstances where teams know what he can do.
"I mean, he's running into a lot of 1.15, 1.2 times to the plate, which he didn't see as much of last year. It's impacting his ability to steal, but it's also giving guys at the plate a better look where pitchers are a little more uncomfortable staying in a slide step. So he still brings a presence there."
Astros: Elmore plays all nine positions
When Jake Elmore trotted out to center field Tuesday, he become the first players in Astros history to play all nine positions in one season.
"I knew I had eight," Elmore said. "Somebody brought it to my attention a couple of weeks ago. I thought it would be cool to get out there. The coaches caught wind of it, and we got the lead and they were like, 'Go make your debut in center.' It was really cool."
The last Major Leaguers to play all nine positions in one season were Scott Sheldon and Shane Halter in 2000. Each accomplished the rare feat in one game.
• In 15 games against the Astros this season, Mike Trout is hitting .339.
• Howie Kendrick has been out of the lineup since Aug. 5 with a sprained left knee and is expected to return when the Angels face the Astros.
"Obviously the timing is something that's going to come with at-bats, but my swing feels good," Kendrick said. "You never know until you get in a game. Timing is the whole thing, and I haven't seen live action in a while. But it'd be just jumping into something I've done my whole life. I'm not expecting a whole lot early on, but once I get back into the swing of things, I'll start to feel better."
William Boor is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.