HOUSTON -- Pirates right-hander Jeff Karstens will miss his next scheduled start on Friday with right shoulder fatigue. He was more sore than normal after lasting only 3 2/3 innings on Sunday in a 7-4 loss at St. Louis.
"We haven't pinpointed anything, but we can go with [shoulder fatigue]," said Pirates manager Clint Hurdle.
Karstens did not throw on Monday and may not throw on Tuesday before seeing how he feels.
"It's not painful. It's just sore, stiff," said Karstens. "It's taken me longer to feel fresh or normal. I don't want to be stupid about it. I understand there's a month left. Right now, to keep me from preventing anything or making anything worse, the best idea is to skip a start.
"I'm not really sure what's going on. We had it checked out. Everything came back negative. It's something I'm going through right now. We'll do all the stuff to try to prevent it from coming back, and hopefully come back after missing a start."
Karstens has pitched 152 innings in 28 games -- 24 starts -- his most innings since 2006.
"Hopefully, skipping a start will give me extra rest and let my shoulder calm down a bit," said Karstens. "Hopefully, this missed start will make me finish the season strong. That's the disappointing part for me. You want to make all your starts throughout the season."
The Pirates didn't name a replacement for Friday's start against the Cubs in Chicago.
Pirates stack lineup with righties vs. Wandy
HOUSTON -- Pirates manager Clint Hurdle's approach to Astros left-hander Wandy Rodriguez on Monday was to have a starting lineup of seven right-handed batters and two switch-hitters.
"We've done it different," said Hurdle. "So today we're going to take our shots at him from the right side and see how that plays out."
Pittsburgh faced Rodriguez for the fourth time this season. Entering Monday, Rodriguez was 1-1 with a 5.30 ERA against Pittsburgh in 2011.
"I've seen Wandy so good so many times," said Hurdle. "This year, we've had a little success.
"He's a good pitcher. When he's got that breaking ball working and command of his fastball, he's a very good left-handed pitcher. There's a lot of teams that would like to have him."
Brandon Wood was in the starting lineup, mainly because of his success against Rodriguez.
Wood, who batted seventh and played first base, was 5-for-7 with two doubles and a home run lifetime against Rodriguez entering Monday's game.
"I don't think there's any one thing -- I've managed to put some decent swings on him," said Wood. "Sometimes you hit some guys and sometimes you don't. When you've had some success, sometimes you just relax and hit."
Wood, who was claimed off waivers from the Angels on April 22, remembers hitting a couple of curveballs, a couple of fastballs and maybe a changeup for his five hits off Rodriguez.
Lee swings in cage for first time since injury
HOUSTON -- Pirates first baseman Derrek Lee took swings in the batting cage on Monday for the first time since being placed on the 15-day disabled list on Aug. 15 with a fractured bone in his left wrist.
A little more than two hours before the game against the Astros, he took about 20 swings as planned.
"I felt good," said Lee. "Hopefully, I'll progress from there. Hopefully, I'll wake up and it still feels good [on Tuesday] and go on from there. Everything is good."
Lee is scheduled to take more swings in the batting cage on Tuesday but isn't sure when he'll return to the lineup.
"There is no timetable," said Lee. "The hand will dictate."
Tuesday's scheduled starter, Charlie Morton, has the second-longest active streak of consecutive at-bats by right-handed opponents without a home run at 329, dating back to Sept. 27, 2010. Atlanta's Jonny Venters has the longest active streak at 384 at-bats.
Outfielder Robbie Grossman and third baseman Elevys Gonzalez of the Bradenton Marauders, the Class A Advanced affiliate of the Pirates, have been named to the Florida State League postseason All-Star team. Grossman leads all of professional baseball in runs with 123. Gonzalez's 79 RBIs are second in the Florida State League.
Richard Dean is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.